Mutate

MTG Mechanic

When you cast a creature spell for its mutate cost, a few things change about how you cast it. First, you pay the mutate cost rather than the mana cost. Second, the spell will require a target. Specifically, a target non-Human creature you own. Humans on Ikoria spend all their energy merely surviving, so their cells just aren't up for the mutation thing, I'm guessing. Mutate can be used only if you're casting the spell. If a creature card with mutate enters the battlefield some other way, it just enters the battlefield.